Lp(a): A Toolkit for Health Care Professionals

9 To Screen or Not to Screen z Family history of premature ASCVD (men, age <55 years; women, age <65 years) not explained by major risk factors z A personal history of premature ASCVD not explained by major risk factors Because themajority of Lp(a) plasma concentration (up to 90%) is influenced by genetics through the LPA gene, 5 relative indications of its measurement are: If a decision is made to measure Lp(a), an Lp(a) ≥50 mg/dL or ≥125 nmol/L may be considered a risk-enhancing factor for ASCVD events.